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Clinically reviewed

Atomoxetine for ADHD

Clinically reviewed by Shamir Patel(GPhC) Last reviewed October 2026

Direct answer

What is atomoxetine and how is it used for ADHD?

Atomoxetine is a non-stimulant medicine (a selective noradrenaline reuptake inhibitor) licensed in the UK for treating ADHD. It increases noradrenaline levels and works gradually, so the full effect may take several weeks. It provides continuous cover rather than wearing off during the day. It is prescribed only after diagnosis, when clinically appropriate, and the dose is adjusted gradually during titration with regular monitoring.

  • Non-stimulant medicine (a selective noradrenaline reuptake inhibitor)
  • Forms: capsules and oral solution
  • Started at a low dose and adjusted during titration
  • Blood pressure, pulse, weight and sleep monitored
  • Never guaranteed — prescribing is a clinical decision

What atomoxetine is

Atomoxetine is a non-stimulant medicine (a selective noradrenaline reuptake inhibitor). It increases noradrenaline levels and works gradually, so the full effect may take several weeks. It provides continuous cover rather than wearing off during the day.

Where it fits in NICE guidance

NICE NG87 sets out the order in which ADHD medicines are usually considered for children, young people and adults, and recommends that treatment is started by a specialist and reviewed regularly. Your prescriber will explain why a particular medicine is suggested for you.

Possible side effects

  • Reduced appetite and nausea
  • Stomach ache
  • Sleep problems or tiredness
  • Increased heart rate and blood pressure
  • Rarely, mood changes or liver problems — report these promptly

Titration and monitoring

Titration means starting at a low dose and adjusting it step by step, usually every one to two weeks, until the benefit outweighs any side effects. At ADHD Path each titration review checks symptoms, side effects, blood pressure, pulse and weight before any change.

Important

This page is general information, not advice about your own treatment. Medicines are only considered after a diagnosis, when clinically appropriate, and are prescribed and adjusted by a qualified prescriber during titration with regular monitoring of blood pressure, pulse, weight, sleep and mood. Never start, stop or change a dose without speaking to your prescriber.

Shared care with your GP is subject to individual GP practice agreement and cannot be guaranteed.

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Frequently asked questions

How long does atomoxetine take to work?

Some benefit may appear within weeks, but the full effect can take up to 8–12 weeks.

Is atomoxetine a controlled drug?

No, it is not a controlled drug.

Can ADHD Path prescribe this medicine?

Our independent prescribers consider medication after diagnosis where clinically appropriate. The choice of medicine is an individual clinical decision and is never guaranteed.

Related questions

Related ADHD Path services

Clinical authorship & review

Mark Thornton-Jones, Specialist ADHD Pharmacist & Independent Prescriber

Written by

Mark Thornton-Jones

MPharm (Liverpool John Moores, 2010), Non-Medical Prescribing (Distinction), CPPE General Practice Pathway, ADHD diagnosis & management (2025) · Specialist ADHD Pharmacist & Independent Prescriber

GPhC 2076283
Shamir Patel, CQC Registered Manager & Clinical Pharmacist

Clinically reviewed by

Shamir Patel

MPharm, Independent Prescriber · CQC Registered Manager & Clinical Pharmacist

GPhC 2049338
Published
11 October 2026
Last reviewed
11 October 2026
Next review
11 October 2027

References

  1. Attention deficit hyperactivity disorder: diagnosis and management (NG87). National Institute for Health and Care Excellence (NICE), 2018, updated 2019. Source
  2. Attention deficit hyperactivity disorder — treatment summary. BNF (NICE). Source
  3. Attention deficit hyperactivity disorder (ADHD) — Treatment. NHS. Source